Drivers have been facing delays this morning on the A338 northbound in Frilford due to an accident on the A415.
The road is now clear following the collision between two cars.
Four passengers involved in the collision received treatment from ambulance staff and one person was taken to the John Radcliffe Hospital in Oxford.
A spokeswoman for South Central Ambulance Service said crews were called to the scene at 9.32am.
She added: "There was a collision on the junction of Frilford Road and Wantage Road involving two vehicles."