Injury issues afflicting many of the world’s leading players promise to make Wimbledon 2018 one of the most open and unpredictable on record.

Here Press Association Sport picks out five potential talking points of the upcoming All England Club Championships.

A step too far for Serena?

Even by Serena Williams’ Herculean standards, an eighth Wimbledon singles title is surely beyond her this year. Williams will head to the All England Club having made an impressive comeback following the birth of her first child. However, she was forced to withdraw prior to her French Open fourth-round clash with Maria Sharapova with an arm injury. All eyes will be on the American as she seeks to seal what would be one of the greatest sporting comebacks of all time.

Roger to reign again?

Will we see this familiar sight again in 2018?
Will we see this familiar sight again in 2018? (Daniel Leal-Olivas/POOL)

While his ‘Fab Four’ rivals limp and scrap their way back to the All England Club, Federer sails imperiously on in search of a 21st grand slam crown. At the age of 36, the Swiss superstar is playing some of the best tennis of his career and will start as favourite to add another title, with key rivals Rafael Nadal, Novak Djokovic and Andy Murray all going through various phases of recuperation from injuries.

Edmund to emerge?

As silly as it may sound, perhaps Andy Murray is not the Briton to watch at Wimbledon this year. In the first phase of his comeback after a year-long absence with a hip injury, surely another Murray grand slam challenge is too much to ask. But Edmund, who usurped Murray as British number one in his absence, has proved his pedigree amongst the elite since reaching this year’s Australian Open semi-final, and it would be no surprise to see him stick around deep into the second week.

Withdraw at your peril

Alexandr Dolgopolov was only able to complete 10 games of his first-round match against Roger Federer last year
Alexandr Dolgopolov was only able to complete 10 games of his first-round match against Roger Federer last year (Adam Davy/PA)

Watch for withdrawals. After a spate of disappointing injury withdrawals last year, Wimbledon has adopted a system which was first tested at the Australian Open in January. Under the system, any player who withdraws prior to a first-round match will receive half of their prize money. But those who play and are subsequently deemed to have under-performed due to a pre-existing issue run the risk of being fined 100 per cent of their purse.

Halep’s rise to continue?

Simona Halep has broken her grand slam duck
Simona Halep has broken her grand slam duck (Adam Davy/PA)

Serena apart, the position of the sport’s dominant female player has been rendered vacant in recent years but there are signs Simona Halep could fit the bill. The feisty Romanian finally made her grand slam breakthrough at this year’s French Open and though her game is evidently better suited to clay, she has reached two successive quarter-finals at the All England Club and could well kick off a dominant spell in the game by following up her Roland Garros success in double-quick fashion.