Keble College has unveiled new plans for a £50m scheme to create a new campus between Woodstock and Banbury Road, Oxford.

The college wants to build on the site of the former Acland private hospital, which the college bought four years ago in a £10.75m deal.

The Keble development would form a new gateway into the city centre from the north and stand across the road from the new £500m Oxford University quarter being created on the old Radcliffe Infirmary site.

Keble unveiled its original plans in February, but withdrew them in the face of strong opposition about key aspects of the scheme, including the demolition of a grade II listed building, designed by the great Victorian architect Sir Thomas Jackson.

In the new plan the building by Jackson, dating from 1897, has been incorporated into the new college quad. Jackson is the architect responsible for many of Oxford’s most famous structures including the Bridge of Sighs.

Roger Boden, bursar of Keble College, said: “The college has taken on board the concerns expressed during the consultation on our earlier proposal. And by preserving the central element of the Jackson building we ensure the work of these two highly original architects can, for the first time, be seen together.”

The Keble scheme is the work of Rick Mather, the architect responsible for the £61m redevelopment of the Ashmolean Museum.

Keble had originally hoped the site would provide accommodation for 250 students, along with seminar rooms and a new multi-disciplinary research facility, created close to the Royal Oak pub on Woodstock Road.

But the redrawn plans may mean a slight reduction in the accommodation for students and a loss of academic and research space.

Tony Joyce, chairman of Oxford Civic Society, said: “We are pleased with the adaptations that Keble has made to the quad that had been originally proposed, and we are happy that it has been possible to retain the building by Jackson.”

But he said doubts remained about the side facing Woodstock Road, with its impact on the Royal Oak pub and new university research buildings.

Keble said the start of work would depend on the success of a college fundraising effort.