Nigel Hume smashed an unbeaten century as Challow & Childrey thrashed Swinbrook by 141 runs in Section C.
Challow rattled up 181-4, Hume hitting 106 not out, then Swinbrook crawled to 40-5.
In Section B, Charlie Fisher (91) and Kieron Foggett (66) helped Witney Swifts to 191-4 against Kidlington.
Graeme Woodward then took 3-4 as Kidlington were shot out for 92.
Minster Lovell beat Combe by four wickets.
Combe rattled up 145-6, Jonathan Bourchier hitting 66.
Minster replied with 146-6, thanks to 49 from Ashley Hubbert.
In Section A, Max Winpenny's 82 not out helped Shipton to 131-2 against Banbury, who replied with 124-5.
Hook Norton 102-6, Horley 96-7.
Shipton 131-2 (M Winpenny 82no), Banbury 124-5 (L Sabin 56).
Section B Combe 145-6 (J Bourchier 66, R Nicholson 39no, E Dunn 3-13), Minster Lovell 146-6 (A Hubbert 49, T Kellie 3-10).
East Oxford 158-6 (Shahbaz Alam 80no, R Simpson 5-30), Bicester & NO 71-4.
Witney Swifts 191-4 (C Fisher 91, K Foggett 66, P Brennan 3-7), Kidlington 92 (G Woodward 3-4).
Freeland 110, Cumnor 113-5 (M Haigh 32no).
Section C Oxford Downs 174-4 (J West 55, G Sandbach 43, C Hunt 31, B Horne 3-28), Minster Lovell Swifts 110-5 (L Day 36).
Shrivenham 122-8 (A Bowles 25, W Snell 25, R Thompson 3-18), Eynsham 114-8 (B Norton 47, Umair Ghazali 34, C Taylor 3-18, R Mills 3-19).
Challow & Childrey 181-4 (N Hume 106no), Swinbrook 40-5.
Section D Kennington 93-6 (J Patel 52no), Horspath 94-2 (T Holmes 28, B Henderson 27).
Dorchester 135-6 (A Bayliss 61, H Latimer 2-13, V Perrera 2-15), Didcot 140-4 (R Cook 81no, J Stimpson 3-17).
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