Broughton & North Newington set up an Oxfordshire Charity Cup quarter-final meeting with Stonesfield with a 2-1 success against AFC Hinksey.
After a goalless first half, Steve Norman fired the hosts ahead, before Alec Hale lobbed a second.
Although Jerome McCalmon hit back from 25 yards, having earlier missed a penalty, Broughton held on.
Horspath eased through with a 4-0 win against Bardwell, thanks to goals from Paul Cooper, Paul Flack, plus substitutes Ben Curtis and Matt Chase.
Goals from Paul Knight, Kori Noonan and Gary Maleachran saw Stonesfield to a 3-2 win at Oakley United in the Ben Turner Cup.
John Armstrong replied with a brace.
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